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JNCASR Scientists Develop Silk-Based Hydrogel Mimicking Pancreas for Diabetes Treatment

Scientists at Jawaharlal Nehru Centre For Advanced Scientific Research (JNCASR) have achieved a significant breakthrough in diabetes treatment with the development of a novel silk-based hydrogel system that mimics the function of the pancreas.


The innovative hydrogel system holds promise for revolutionizing insulin delivery for individuals with Type 1 and advanced stage Type 2 diabetes, offering a more efficient and responsive approach to managing blood glucose levels.


Led by Prof. T. Govindaraju and his team from the Bio-organic Chemistry Laboratory, New Chemistry Unit at JNCASR, the research was inspired by the success of a previous study involving passive insulin release using silk protein fibroin.


Building on their previous findings, the team modified the silk protein to create a sophisticated system capable of responding to glucose levels in the blood, ensuring a continuous and controlled supply of insulin similar to the natural function of the pancreas.


This groundbreaking development holds the potential to significantly enhance the quality of life for individuals living with diabetes by providing a more effective and personalized approach to insulin therapy. The research represents a remarkable advancement in the field of diabetes management, offering hope for improved treatment outcomes in the future.